This book seeks to resolve an issue that has divided psychoanalysts and other scholars of aggression for decades, namely the nature of aggression. The work expands and unifies the Freudian drive-based explanation of aggression into contemporary psychoanalytic theory and practice and brings Freudian theory into the 21st Century.

This book seeks to resolve an issue that has divided psychoanalysts and other scholars of aggression for decades, namely the nature of aggression. The work expands and unifies the Freudian drive-based explanation of aggression into contemporary psychoanalytic theory and practice and brings Freudian theory into the 21st Century.

LANGUAGE NOTE | Document text in Chinese; abstract also in English. ECMO是一項高風險、高創傷、高消耗的創新技術，它能夠為新冠病毒肺炎重症患者提供挽救性治療°ECMO的治療目標是幫助患者恢復心肺功能，或者橋接最終治療，包括器械植入，或者器官移植等。然而，容易被忽視的 事實是，ECMO挽救了一些患者的生命，但也可能讓那些沒有康復機會的患者陷入醫療困境。於是，ECMO的臨床應用不得不面對一些反對意見，包括嚴重併發症危害患者生命安全、無效治療導致技術失敗，以及大量佔用資 源損害醫療公平等。ECMO技術的臨床應用應該在尊重生命價值和患者意願的基礎上，合理設置治療目標、確立可接受退出標準、妥善處理患者意願與ECMO設備撤除困境之間的倫理衝突，建立適度倫理框架以合理控制醫療 干預的邊界。 Characterized by high risk, high trauma and high consumption, Extra-Corporeal Membrane Oxygenation (ECMO) is an innovative technology that can be used as salvage therapy for COVID-19 patients. ECMO treatment can help restore patients' cardiopulmonary function or can bridge their final treatment, including device implantation or organ transplantation. However, although ECMO saves some patients' lives, it can also leave those with no chance of recovery in a medical dilemma. ECMO (...) is thus controversial: it is criticized for technical failures and ineffective treatments, and its use raises questions about medical equity. This paper argues that the clinical application of ECMO technology should be based on a respect for the value of life and the will of patients, reasonably set therapeutic goals, acceptable withdrawal criteria, proper management of the conflict between patients' desires and the medical dilemma, and the establishment of an ethical framework to control the limits of medical intervention. (shrink)

Our understanding of language, its origins and subsequent evolution, is shaped not only by data and theories from the language sciences, but also fundamentally by the biological sciences. Recent developments in genetics and evolutionary theory offer both very strong constraints on what scenarios of language evolution are possible and probable, but also offer exciting opportunities for understanding otherwise puzzling phenomena. Due to the intrinsic breathtaking rate of advancement in these fields, and the complexity, subtlety, and sometimes apparent non-intuitiveness of the (...) phenomena discovered, some of these recent developments have either being completely missed by language scientists or misperceived and misrepresented. In this short paper, we offer an update on some of these findings and theoretical developments through a selection of illustrative examples and discussions that cast new light on current debates in the language sciences. The main message of our paper is that life is much more complex and nuanced than anybody could have predicted even a few decades ago, and that we need to be flexible in our theorizing instead of embracing a priori dogmas and trying to patch paradigms that are no longer satisfactory. (shrink)

The first of its kind to thoroughly cover language technology at all levels and with all modern technologies this book takes an empirical approach to the ...

Hannah Arendt first argued the continuities between the age of European imperialism and the age of fascism in Europe in 'The Origins of Totalitarianism'. This text uses Arwndt's insights as a starting point for further investigations into the ways in which race, imperialism, slavery and genocide are linked.

Viewing workplace deviance within a victim precipitation framework, we explore how abusive supervisors target subordinates low in core self-evaluations to explain when such employees respond by engaging in workplace deviance. We theorize that employees who are lower in CSE receive more abusive supervision, which generates subsequent harmful reactions toward supervisors, peers, and the organization. This occurs primarily when employees lack sufficient cognitive resources in dealing with supervisor abuse. We test, replicate, and extend our theoretical model in three empirical studies. Results (...) demonstrate that lower employee CSE drew more abusive supervision and led low-CSE employees to exhibit workplace deviance. This abusive supervision mediation effect was stronger for employees with comparatively lower cognitive ability levels. The findings are discussed with regard to theoretical and ethical issues in confronting employee abuse. (shrink)

Emotion regulation (i.e. either up- or down-regulating affective responses to emotional stimuli) has been shown to modulate long-term emotional memory formation. Further, research has demonstrated that the emotional aspects of scenes are preferentially remembered relative to neutral aspects (known as the emotional memory trade-off effect). This trade-off is often enhanced when sleep follows learning, compared to an equivalent period of time spent awake. However, the interactive effects of sleep and emotion regulation on emotional memory are poorly understood. We presented 87 (...) participants with pictures of neutral or negative objects on neutral backgrounds paired with instructions to either increase or decrease their emotional response by altering personal relevance, or to passively view the stimuli. Following a 12 h period of sleep or wakefulness, participants were tested for their memory of objects and backgrounds separately. Although we replicated the emotional memory trade-off effect, no differences in the magnitude of the trade-off effect were observed between regulation conditions. Sleep improved all aspects of memory, but it did not preferentially benefit memory for emotional components of scenes. Irrespective of a period of sleep or wake following encoding, findings suggest emotion regulation during encoding did not influence memory for emotional items at a 12-hour delay. (shrink)

This paper presents an enhanced ontology formalization, combining previous work in Conceptual Structure Theory and Order-Sorted Logic. Most existing ontology formalisms place greater importance on concept types, but in this paper we focus on relation types, which are in essence predicates on concept types. We formalize the notion of ‘predicate of predicates’ as meta-relation type and introduce the new hierarchy of meta-relation types as part of the ontology definition. The new notion of closure of a relation or meta-relation type is (...) presented as a means to complete that relation or meta-relation type by transferring extra arguments and properties from other related types. The end result is an expanded ontology, called the closure of the original ontology, on which automated inference could be more easily performed. Our proposal could be viewed as a novel and improved ontology formalization within Conceptual Structure Theory and a contribution to knowledge representation and formal reasoning (e.g., to build a query-answering system for legal knowledge). (shrink)

Mrs. P is a seventy‐six‐year old woman with osteoporosis and a failed left hip prosthesis. In addition, she has severe chronic asthmatic bronchitis. The management of her lung disease has been hampered by her allergy to theophylline, which is one of the mainstays of treatment. As a result, she has had increasing difficulty walking and confinement to a wheelchair is imminent. When surgery to replace the prosthesis was recommended, Mrs. P expressed concern about the possibility of ending up after the (...) operation dependent on a ventilator, possibly comatose. She feared that her resources would be depleted for medical expenses. Little or nothing would be left to pass on to her children. She was willing to have an operation only if she could prepare a legal document that, in the event of prolonged ventilator dependence, would require her physician to remove her from the ventilator after a specified time (for example, two weeks). Should the surgeon agree to be bound by Mrs. P's instructions, or should he refuse her request even if doing so means that she will not have the surgery that might prevent increasing disability? (shrink)

We report on the deliberations of an interdisciplinary group of experts in science, law, and philosophy who convened to discuss novel ethical and policy challenges in stem cell research. In this report we discuss the ethical and policy implications of safety concerns in the transition from basic laboratory research to clinical applications of cell-based therapies derived from stem cells. Although many features of this transition from lab to clinic are common to other therapies, three aspects of stem cell biology pose (...) unique challenges. First, tension regarding the use of human embryos may complicate the scientific development of safe and effective cell lines. Second, because human stem cells were not developed in the laboratory until 1998, few safety questions relating to human applications have been addressed in animal research. Third, preclinical and clinical testing of biologic agents, particularly those as inherently complex as mammalian cells, present formidable challenges, such as the need to develop suitable standardized assays and the difficulty of selecting appropriate patient populations for early phase trials. We recommend that scientists, policy makers, and the public discuss these issues responsibly, and further, that a national advisory committee to oversee human trials of cell therapies be established. **NB we did not reccommend a NAC, we think it might be appropriate**. (shrink)

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

Director compensation can potentially represent an ethical minefield. When faced with supporting strategic decisions that can lead to an increase in director pay, directors may consider their own interests and not solely those of the shareholders to whom they are legally bound to represent. In such cases, directors essentially become agents, rather than those installed to protect principals (shareholders) from agents. Using acquisitions as a study context, we employ a matched-pair design and find a statistically significant difference in outside director (...) compensation between acquiring and control firms. Outside directors of acquiring firms earn more than twice as much as their counterparts in the matched-sample. (shrink)

1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

Preface Part One Buddhism and Phenomenology Ch.1Buddhism and Phenomenology Ch.2 Husserl and Merleau-Ponty Part Two The Four Basic Buddhist Models in India Introduction Ch.3 Model One: The Five Skandhas Ch.4 Model Two: Pratitya-samutpada Ch.5 Model Three: Tridhatu Ch.6 Model Four: Sila-Samadhi-Prajna Ch.7 Asamjni-samapatti and Nirodha-samapatti Ch.8 Summary of the Four Models Part Three Karma, Meditation, and Epistemology Ch.9 Karma Ch.10 Madhyamikan Issues Ch.11 The Privilaging of Prajna-paramita Part Four Trimsika and Translations Ch.12 Texts and Translations Part Five The Ch’eng Wei-Shih (...) Lun and the Problem of Psychosophical Closure: Yogacara in China Ch.13 Ch.14 Seven Trajectories Ch.15 The Legend of the Transmission of the Ch’eng Wei-Shih Lun Ch.16 Alterity: Parinama Ch.17 Why Consciousness in Not Empty Ch.18 On Rupa Ch.19 Externality Ch.20 The Four Conditions Ch.21 Mirror Knowing: Soteric Alterations Ch.22 Language, Avijnapti-Rupa and Vijnapti-Rupa Ch.23 Is What is Ultimately Real Itself Ultimately Real? Conclusions Appendices Bibliography Index. (shrink)

In this essay I argue that in some sense legal philosophy, at least as the term is now understood among analytic jurisprudents in the Anglophone world, is to a large extent a creation of H. L. A. Hart’s work. It is with him that the search for the concept or the nature of law was one established as an independent object of inquiry, that consciously tried to avoid moral or political questions. In framing the province of jurisprudence in this way (...) Hart not only departed from the work of Thomas Hobbes and Jeremy Bentham, whose political commitments are clear, but also from the seemingly much closer enterprise of John Austin. After demonstrating this difference between Austin’s enterprise and Hart’s, I criticize the direction legal philosophy has taken following Hart’s lead.Resumen:En este ensayo se plantea la idea de que en cierto modo la filosofía del derecho —al menos en la forma en que es entendida entre los filósofos analíticos del mundo angloparlante— es en gran medida una invención de H. L. A. Hart. Con la obra de Hart, en efecto, la búsqueda del concepto o naturaleza del derecho, se ha consolidado como un objeto de investigación independiente, que conscientemente pretende deslindarse de las cuestiones políticas o morales. Al definir el campo de estudio de la filosofía del derecho en este sentido, Hart no sólo se aparta del trabajo de Thomas Hobbes y de Jeremy Bentham, cuyos compromisos políticos son evidentes, sino también del proyecto aparentemente más cercano de John Austin. Después de señalar la diferencia entre los proyectos de Austin y de Hart, el autor pone en cuestión la dirección que ha tomado la filosofía del derecho al ser encabezada por Hart. (shrink)

In Jacobsen, M.H. (ed.): Sociologies of the Unnoticed. Palgrave/Macmillan, 2008.

Dominic Lopes proposes that seeing-in admits of kinds. He thus suggests five ways of seeing-in that he feels do justice to the variety of pictorial representations. More recently Dan Cavedon-Taylor has argued that the space of seeing-in marked out by Lopes is incomplete, and thus proposes a sixth kind of seeing-in that fits neatly into the taxonomy. I argue that the phenomenon of seeing-in does not divide in as many ways as Lopes and Cavedon-Taylor propose. I show that the purported (...) cases of pseudo-design seeing do not demonstrate that actual design properties are not experienced and as such these cases can be captured by the other ‘ways of seeing-in’ that Lopes identifies. I also argue against the claim that actualism is a distinct kind of seeing-in. Thus the space of seeing-in ought to be significantly reduced. (shrink)

It is natural to think of legal positivism and jurisprudential naturalism as intellectually allied ideas. Legal positivism is associated with the idea that law is a matter of social fact; naturalism is a philosophical tenet that, among other things suggests the importance of scientific findings and methods to philosophy. At the very least, there seems to be a close family resemblance between the two views. In this essay, I challenge this view from a naturalistic perspective. I show that the best-known (...) proponents of legal positivism in the twentieth century all rejected naturalism. I dedicate most of my discussion to H.L.A. Hart’s version of legal positivism, as it appears superficially friendly to naturalism. I show that throughout his career and in writings on a wide range of topics, Hart consistently argued against the applicability of the methods of science to the explanation of social phenomena. This is not a small matter: I argue that it is this anti-naturalistic stance that contributed to his descriptively faulty account of adjudication. After reviewing more briefly the work of other leading legal positivists, I argue in my conclusion that those seeking to advance a naturalistic approach to law should turn their backs of much of twentieth-century legal positivism, which in various guises has been hostile to naturalism. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

The vision of integrating artificial intelligence in education is part of an ongoing push for harnessing digital solutions to improve teaching and learning. Drawing from Jasanoff (Future imperfect: Science, technology, and the imaginations of modernity. In S. Jasanoff, & S. H. Kim (Eds.), Dreamscapes of modernity: Sociotechnical imaginaries and the fabrication of power (pp. 1–33). The University of Chicago Press, 2015. 10.7208/9780226276663) and Hasse (Socratic ignorance in processes of learning with technology. In H. Bound, A. Edwards, & A. Chia (Eds.), (...) Workplace learning for changing social and economic circumstances (pp. 76–90). Routledge, 2023), this paper deliberates on how sociotechnical imaginaries are interrelated to the implications of new technologies, such as AI, in education. Complicating Hasses’s (Socratic ignorance in processes of learning with technology. In H. Bound, A. Edwards, & A. Chia (Eds.), Workplace learning for changing social and economic circumstances (pp. 76–90). Routledge, 2023) call for the development of Socratic ignorance to consider our predispositions about new technologies and open new prospects of thought, this paper revisits postphenomenology (Ihde, Technology and the lifeworld: From garden to earth. Indiana University Press, 1990; Ihde, Postphenomenology: Essays in the postmodern context. Northwestern University Press, 1993; Ihde, Postphenomenology and technoscience. The Peking University lectures. State University of New York Press, 2009) and Feenberg’s (Critical theory of technology, Oxford University Press, 1991; Between reason and experience, MIT Press, 2010; Techne: Res Philos Technol 24:27–40, 2020) critical constructivist theories. While embracing the notion of Socratic ignorance, this paper stresses the importance of developing a nuanced understanding of technology that realizes its lack of neutrality and supports the creation of a deeper understanding of how knowledge is produced, deployed, and interpreted in the digital age. Thus, this paper argues that an amalgam of Hasse’s call for advancing Socratic ignorance combined with postphenomenology and critical constructivism can support students in developing a critical understanding of technology and opening new landscapes of imaginaries. (shrink)

Au renouveau indéniable de la théologie de la création, ne semble pas correspondre, dans l’expérience d’un bon nombre de chrétiens de notre temps, un intérêt égal pour l’affirmation de la création du monde ou de Dieu créateur. Comment expliquer cette disparité ? La croyance à la création revêt deux formes, l’une faible, celle du théisme, l’autre forte, celle de la foi scripturaire liée à l’Alliance, et il semble que la seconde cherche à assumer la première comme une voie sapientielle de (...) portée universelle ; mais la foi de nombreux chrétiens ne paraît même pas impliquer cette croyance faible. Cet oubli appauvrit sans doute leur foi, mais peut s’expliquer : la sécularisation a produit un effacement de la notion de création, qui a perdu son évidence culturelle, la question de l’origine est laissée à la science, le croyant trouve Dieu dans la proximité du présent et ne le cherche plus dans l’espace originaire, et des attitudes croyantes, autrefois liées à cette notion, s’expriment aujourd’hui autrement sans altération de la foi. La théologie aurait avantage à analyser le lien de la création à la culture, et à expliciter le rôle qu’y joue l’Esprit Saint dans une perspective mystique d’anéantissement ou de « décréation ».Despite an undeniable renewal of creation theology, a good number of contemporaneous Christians do not seem to have the same interest in affirming the world’s creation or a God creator. How can this disparity be explained ? Belief in creation takes on two forms : a weak one of theism and a strong one of scriptural faith tied to the Covenant. It seems that the second tries to assume the first as a sapiential way with universal import. The faith of numerous Christians, however, does not seem to even imply this weak belief. Without doubt, this omission impoverishes their faith but can be explained : secularization wiped out the idea of creation when it lost its cultural importance. The question of origins is left to science, ; the believer finds God in the proximity of the present and no longer looks for the original space. It is also true that believing attitudes, which were tied to this notion in the past, express themselves today in another way, without changing the faith. Theology would be better off if it analysed the connection of creation to culture and make explicit the role that the Holy Spirit plays in the mystical perspective of annihilation or of “de-creation”. (shrink)